Abstract
Acute colonic pseudoobstruction (ACPO), often referred to as Ogilvie syndrome, is
a clinical entity characterized by severe colonic distension (adult acute megacolon)
in the absence of mechanical obstruction. It can result in abdominal ischemia and
perforation if left untreated. This article discusses the epidemiology and current
pathophysiologic theories of ACPO as well as the clinical presentation and diagnostic
modalities utilized to identify the disease. In addition, this article describes the
current treatment options for ACPO, which range from conservative medical therapy,
therapeutic endoscopy, to subtotal colectomy.
Keywords
colonic ileus - acute colonic pseudoobstruction - Ogilvie syndrome - large bowel obstruction